BIOCHEMICAL STUDIES OF VIRUS-INFECTED CELLS*

Biochemical studies of virus-infected cells.

The orientation imposed by the subject of this monograph leads us to emphasize those aspects of the chemistry of infection that may serve our understanding of the morphology of infection. Indeed, much of the effort expended in this field has been justified under a hypothesis that the genesis of the cytopathic effect is a biochemical lesion. How that lesion is inflicted by the virus, the ensuing...

Macromolecular synthesis in cells infected with Herpes simplex virus

Biochemical Studies of Virus Reproduction

Direct chemical evidence has shown that the infecting bacterial virus particle is extensively broken down during the reproductive process (1,2). This finding supports the interpretation of various studies of bacteriophage reproduction by geneticists, who have postulated that the virus is broken down to smaller units shortly after infection (3-6). The disruption of the virus particle upon infect...

Biochemical Studies of Virus Reproduction

Despite frequent speculation concerning the mode of action of viruses, few biochemical studies of the virus-host cell relationship have been undertaken, and the sequence of steps in virus multiplication remains largely unknown. Any tenable theory of virus reproduction must consider both the r&e and the fa,te of the original infecting virus particle, and, at present, little evidence is available...

Rna Complexes in Vesicular Stomatitis Virus Infected L-cells Studies